KIT (CD117) Expression in a Subset of Non-Small Cell Lung Carcinoma (NSCLC) Patients
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چکیده
منابع مشابه
KIT (CD117) Expression in a Subset of Non-Small Cell Lung Carcinoma (NSCLC) Patients
We have previously described the expression of CD44, CD90, CD117 and CD133 in NSCLC tumors, adjacent normal lung, and malignant pleural effusions (MPE). Here we describe the unique subset of tumors expressing CD117 (KIT), a potential therapeutic target. Tumor and adjacent tissue were collected from 58 patients. Six MPE were obtained before therapy. Tissue was paraffin embedded for immunofluores...
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BACKGROUND The aim of this study was to determine the incidence and role of CD117 (c-KIT) overexpression as a predictive/prognostic marker in extensive-stage small-cell lung carcinoma (ESSCLC). We performed a retrospective study on subjects with a biopsy-proven diagnosis of ESSCLC. PATIENTS AND METHODS A chart review for demographic and clinical data was performed on patients with ESSCLC diag...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0052885